Airdrops are random events that can occur at any time, though they occur more frequently when the player is low on energy (to encourage coin usage).
The box contains randomized loot (usually has at least 1 half-durability weapon, rest are random parts).
The area is also a good source of Pine Logs.
If you leave and come back (within its spawn time) the loot will not change/reset so you can loot it clean if you have the energy and time.
The area is guarded by one Floater Bloater and at least two Toxic Spitters. So it is best to come there armed with a high damage melee. (Be careful, because the Toxic Spitter will make attention and try to kill you).